7003APOLLO-NCT03242642OpenTranscatheter Mitral Valve Replacement with the
Medtronic Intrepid TMVR System in patients
with severe symptomatic mitral regurgitation
APOLLO TrialEvaluate whether TMVR is non-inferior to conventional mitral surgery with respect to composite endpoint rate of all-cause mortality, all stroke, reoperation (or reintervention) and cardiovascular hospitalization at one year in patients with severe symptomatic native mitral regurgitation.NCT03242642IndustrialAdultTreatmentDevice: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR); Device: Surgical Mitral Valve Replacement (SMVR)PivotalGlobalMitral regurgitationRelevant Condition or Disease: Mitral Valve RegurgitationShults, Christian; Waksman, RonMedstar Washington Hospital CenterMCRN - Wash Interventional2026.1.0 Build 16 <a href="https://advarra.com" target="_blank">© 2026 Advarra, Inc.</a>