<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>6185</id><no>JENAVALVE-AS-NCT02732691</no><status>Open</status><title>JenaValve Pericardial TAVR System Aortic Stenosis Study</title><objective>The purpose of this research study is to collect information about a new treatment for severe aortic stenosis, which affects the aortic valve in the heart. Aortic stenosis is a narrowing of the aortic valve opening, which decreases blood flow from the heart and causes symptoms such as chest pain, fainting and shortness of breath. The preferred treatment for severe aortic stenosis is aortic valve replacement surgery.</objective><secondary_protocol_no>P02C220_JV06EFS_CIP</secondary_protocol_no><nct_id>NCT02732691</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><treatment>Device: JenaValve Pericardial TAVR System</treatment><disease_site>Diseases Of The Circulatory System</disease_site><lay_description>Relevant Conditions/ Diseases: Aortic Stenosis Heart Valve Diseases&#xD;
Heart Diseases&#xD;
Cardiovascular Diseases&#xD;
Ventricular Outflow Obstruction</lay_description><PI>Waksman, Ron</PI><institution>Medstar Washington Hospital Center</institution><management_group>MCRN - Wash Interventional</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>