<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>3941</id><no>AMPLATZER-PFO-NCT03309332</no><status>Open</status><title>AMPLATZER PFO Occluder Post Approval Study (PFO PAS)</title><objective>The purpose of this single arm, multi-center study is to confirm the safety and effectiveness of the AMPLATZER; PFO Occluder in the post Approval Setting.</objective><secondary_protocol_no>SJM-CIP-10187 Ver.A</secondary_protocol_no><nct_id>NCT03309332</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><treatment>Device: AMPLATZER; PFO Occluder; Implantation of the AMPLATZER; PFO Occluder in the PFO&#xD;
</treatment><phase>PAS</phase><scope>Global</scope><disease_site>Stroke</disease_site><lay_description>Relevant Conditions / Diseases: Stroke and Patent Foramen Ovale.</lay_description><PI>Satler, Lowell</PI><institution>Medstar Washington Hospital Center</institution><management_group>MCRN - Wash Interventional</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>