<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>17178</id><no>ETCTN-10716-NCT07147231</no><status>Open</status><title>A Phase 1 and Randomized Phase 2 Trial of Pidnarulex (CX-5461) and Cemiplimab (REGN2810) in Refractory Microsatellite Stable Colorectal Cancer</title><secondary_protocol_no>10716</secondary_protocol_no><nct_id>NCT07147231</nct_id><sponsor_type>National</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>II</phase><scope>National</scope><disease_site>Other</disease_site><PI>Weinberg, Benjamin</PI><institution>Georgetown University Medical Center : Isabel Frye; Lombardi Comprehensive Cancer Center : Isabel Frye</institution><oncology_group>Gastrointestinal<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>Lombardi Comprehensive Cancer Center (LCCC)</management_group><item><contact_id>17359</contact_id><item_description>Isabel Frye</item_description><js_safe_str>Isabel Frye</js_safe_str><email>if151@georgetown.edu</email></item></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>