<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>16633</id><no>TNG462-C102-NCT06922591</no><status>Open</status><title>A Phase 1/2, Multicenter, Open-Label Study to Evaluate Safety, Tolerability &amp; Antitumor Activity of TNG462 in Combination With Other Agents in Patients With Pancreatic or Non-Small Cell Lung Cancer With MTAP Loss &amp; RAS Mutation</title><secondary_protocol_no>TNG462-C102</secondary_protocol_no><nct_id>NCT06922591</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>I/II</phase><disease_site>Other</disease_site><PI>Noel, Marcus</PI><institution>Georgetown University Medical Center : Princess Jones; Lombardi Comprehensive Cancer Center : Princess Jones</institution><oncology_group>Gastrointestinal<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>Lombardi Comprehensive Cancer Center (LCCC); Oncology PFS</management_group><item><contact_id>14509</contact_id><item_description>Princess Jones</item_description><js_safe_str>Princess Jones</js_safe_str><email>paj24@georgetown.edu</email></item></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>