<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>16264</id><no>MK-2400-01A-00-NCT06863272</no><status>Open</status><title>MK-2400-01A Substudy: A Phase 1/2, Open-label Umbrella Substudy of MK 2400-U01 Master Protocol to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan-based Treatment Combinations or Ifinatamab Deruxtecan Alone in Participants with Metastatic Castration -resistant Prostate Cancer (mCRPC) (IDeate-Prostate02)</title><secondary_protocol_no>MK-2400-01A</secondary_protocol_no><nct_id>NCT06863272</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>I/II</phase><scope>Global</scope><disease_site>Prostate</disease_site><PI>Rapisuwon, Suthee</PI><institution>MedStar Health and GUMC</institution><oncology_group>Genito-urinary<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>MHRI Washington Cancer Institute</management_group><item><contact_id>16794</contact_id><item_description>Felobateer Hanna</item_description><js_safe_str>Felobateer Hanna</js_safe_str><email>felobateer.a.hanna@medstar.net</email></item></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>