<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>15812</id><no>3082-CL-0101-NCT05382559</no><status>Open</status><title>A Phase 1 Study of ASP3082 in Participants With Previously Treated Locally Advanced or Metastatic Solid Tumor Malignancies With KRAS G12D Mutation</title><secondary_protocol_no>3082-CL-0101</secondary_protocol_no><nct_id>NCT05382559</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>I</phase><disease_site>Other</disease_site><PI>Noel, Marcus</PI><institution>Georgetown University Medical Center : Shannon Raue; Lombardi Comprehensive Cancer Center : Shannon Raue</institution><oncology_group>Phase I<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>Lombardi Comprehensive Cancer Center (LCCC); Oncology PFS</management_group><item><contact_id>16186</contact_id><item_description>Shannon Raue</item_description><js_safe_str>Shannon Raue</js_safe_str><email>sr1657@georgetown.edu</email></item></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>