<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>14488</id><no>VLX-301</no><status>Open</status><title>A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Sclerosing.Cholangitis (VISTAS.</title><nct_id>NCT04663308</nct_id><sponsor_type>Industrial; Institutional</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>II</phase><disease_site>Other</disease_site><PI>Smith, Coleman</PI><institution>MedStar Health Fairfax; Medstar Washington Hospital Center</institution><management_group>MedStar Medical &amp; Surgical Research Network</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>