<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>14328</id><no>MK-7902-014-03</no><status>Open (affiliates only)</status><title>A Phase 3, Randomized Study to Evaluate the Efficacy and Safety of &#xD;
Pembrolizumab (MK-3475) + Lenvatinib (E7080/MK-7902) + Chemotherapy Compared &#xD;
with Standard of Care as First-line Intervention in Participants with Metastatic Esophageal &#xD;
Carcinoma</title><nct_id>NCT04949256</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><phase>III</phase><scope>National</scope><disease_site>Esophagus</disease_site><PI>Tesfaye, Anteneh</PI><institution>Medstar Washington Hospital Center</institution><oncology_group>Gastrointestinal<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>MHRI Washington Cancer Institute</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>