<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>10823</id><no>TRIOMPHE-NCT04471909</no><status>Open</status><title>A Multi-Arm, Multi-Center, Non-Randomized, Prospective, Clinical Study to Evaluate the Safety and Effectiveness of the NEXUS&#x99; Aortic Arch Stent Graft System in Treating Thoracic Aortic Lesions Involving the Aortic Arch</title><objective>Prospective, non-randomized, multi-center clinical investigation of the NEXUS&amp;#8482; Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with a brachiocephalic trunk native landing zone.</objective><nct_id>NCT04471909</nct_id><sponsor_type>Industrial</sponsor_type><age_group>Adult</age_group><treatment_type>Treatment</treatment_type><treatment>Device: NEXUS Aortic Stent Graft System&#xD;
</treatment><disease_site>Diseases Of The Circulatory System</disease_site><lay_description>This study investigates the following condition or disease: Aortic Dissection&#xD;
Aortic Aneurysm&#xD;
Intramural Hematoma&#xD;
Penetrating Aortic Ulcer</lay_description><PI>Nissen, Alexander</PI><institution>Medstar Washington Hospital Center</institution><management_group>MCRN - Peripheral Vascular</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>