<?xml version="1.0" encoding="UTF-8"?><protocol_summary><protocol><id>10449</id><no>2018-0439</no><status>Open</status><title>A Randomized Trial of Proactive Outreach and Streamlined Genetic Education in BRCA Families</title><objective>The primary goal of this research is to test a web-based genetic education intervention that is designed to educate men and women from hereditary cancer families about the personal relevance of genetic testing in order to help them male decisions about whether to pursue genetic testing. We will test this intervention against standard care for men and women from hereditary cancer families. The web-based educational intervention includes all of the information typically covered during genetic counseling. As a result, after completing the education intervention, participants can proceed directly to a brief telephone call with a genetic counselor followed by testing if they choose. A baseline survey will be administered prior to randomization and then follow-up surveys will be administered at 1-month and 6-months post-randomization. Primary outcomes will be completion of genetic counseling, uptake of genetic testing, genetic test results and quality of life.&#xD;
</objective><secondary_protocol_no>1 R01 CA223606-01A1</secondary_protocol_no><nct_id>NCT03544983</nct_id><sponsor_type>National</sponsor_type><age_group>Adult</age_group><treatment_type>Health Services Research</treatment_type><treatment>Behavioral: Web + Streamlined Telephone Genetic Counseling</treatment><phase>N/A (Cancer Control) (Cancer Prevention)</phase><cancer_control>Y</cancer_control><cancer_prevention>Y</cancer_prevention><disease_site>Breast</disease_site><lay_description>BRCA1 Mutation&#xD;
BRCA2 Mutation</lay_description><PI>Schwartz, Marc</PI><institution>Dana-Farber Cancer Institute; Inova Schar Cancer Institute; Lombardi Comprehensive Cancer Center; Medstar Franklin Square Medical Center</institution><oncology_group>Population Science<DOWG_name>Oncology Group</DOWG_name></oncology_group><management_group>Lombardi Comprehensive Cancer Center (LCCC)</management_group></protocol><sipVersion>2026.1.0 Build 16</sipVersion><copyright> &lt;a href="https://advarra.com" target="_blank"&gt;&amp;copy; 2026 Advarra, Inc.&lt;/a&gt; </copyright></protocol_summary>